The pandemic and stressful lifestyle have great impact not just on our health but also on our appearance. Inna Orlova, co-founder of the leading Cyprus wellness brand Kypwell, shared with “Successful Business” how consumer preferences in cosmetology have changed recently and what the body needs to maintain beauty and health.
How do you see the year 2024? What new technologies and innovations in beauty and health do you consider most important today?
I think that in the beauty industry, the world has been divided into “pre-COVID” and “post-COVID.” The same has happened with consumer mentality. If the leading philosophy before the pandemic was “beauty at any cost,” COVID has seriously changed consumer views. Now, enormous attention is paid to the origin and the safety of skincare ingredients, their impact on health. It can be said that health is the new wealth in the modern world.
Following modern researches, it has become clear that more than 80% of women’s overweight issues are related to insulin resistance – an excess of glucose – the energy they receive. This is the cause of many other problems, including autoimmune diseases.
In Cyprus, we have two studios, in Limassol and Nicosia. We can see that thyroid disease is a prevalent issue of the modern woman, especially among our Cypriot clients.
In recent years, our eco-products have become even more in demand. Because people are looking for an ecological product, created using plant-based on bio-actives, not synthetic means. Natural ingredients have proven their effectiveness over centuries, unlike synthetic beauty products, the long-term consequences of which are still unknown to us.
Another factor affecting changes in our industry is mental health. More and more people in the so-called “civilized” world are concerned about their emotional state. Therefore, soothing phyto-teas and anti-stress ingredients in cosmetics are attracting increasing consumer interest.
Do you grow and produce all your products in Cyprus?
Yes, we launched our company 9 years ago, based on over 40 years of research and development by the Head of our laboratory professor A.Katsos (PhD biochemistry) and an international team of doctors, including oncologists and technologists. Cyprus is an absolutely unique place for growing medicinal herbs. This was mentioned even before our era by Pliny the Elder, who considered Cyprus the best place in the Mediterranean for cultivating medicinal herbs.
This is mainly due to the volcanic soil on the island, a unique climate with a very high number of sunny days per year, etc. All this, combined with the absence of harmful manufacturing, makes Cypriot medicinal herbs among the best in the world.
The quality of medicinal herbs is assessed by the volume of essential oil they contain. The higher the oil content, the greater the effect the herb has on the human body. In Cyprus, herbs with the highest volume of essential oil in the Mediterranean region grow. They are more potent than in Greece, Turkey, and other Mediterranean countries in this respect.
Based on the latest research in aesthetics and beauty, what innovations do you foresee in cosmetology and skincare?
The market will move in three main directions – genetic developments, integrative cosmetology, and microbiome. Scientists are already developing mechanisms to control bacterial colonies on the face, for example, in the treatment of acne.
Regarding genetics, each person has a certain predisposition in terms of collagen, elastin, vitamin D. We’re talking about some changes in genes, so-called polymorphisms. Personalized cosmetics based on genetics is the future.
Integrative cosmetology is the future of beauty services. Our company has always been a market innovator, and our more than 23 international awards confirm this, so we are the first to start developing integrative cosmetology in Cyprus. In short, integrative cosmetology is the correction of appearance through modifying health from within.
In Cyprus, for example, many are mistaken in thinking that skin pigmentation is due to insufficient use of sun protection. In reality, pigmentation is directly related to iron deficiency and various microelements in the body, as well as the functioning of the thyroid gland.
This is the essence of integrative beauty. When we see some problems on the face, it means that the body is already sending us signals, and these problems need to be solved from the inside.
What would you like to emphasize for our readers, summarizing the interview?
I want to reiterate the importance of caring for both your physical and mental health, especially in our extremely stressful times. Many chronic illnesses in humans arise precisely because of an improper lifestyle – the modern “diet” with an abundance of fructose and alcohol has replaced the traditional Mediterranean diet, lack of quality sleep, absence of balance between work and personal life, etc. All these lead to the undermining of human health. It’s very important to minimize the number of toxins in our life and strive to use natural organic products, and this includes cosmetics and household chemicals as well.
Concluding our conversation, I would like to emphasize once again that it’s impossible to become truly beautiful without taking care of your health and mental well-being.
Inna Orlova
Chairwoman, Co-Founder of Kypwell, Integrative Nutrition Health Coach, Chopra Health & Ayurveda Instructor. Inna gained an MBA in strategic marketing management and has over 25 years’ experience in entrepreneurship, business consulting, as well as health & wellness coaching with focus on metabolic health and insulin resistance.
What is happening with rental property prices? What kind of property is in highest demand? What does the future hold for Cyprus’ real estate market? “Successful Business” spoke with Cypriot real estate expert and leader of several projects, Anfisa Chernaya.
Can you tell us what is happening in the Cypriot real estate sector? Where is everything heading, how is the market changing, are there any new requests that developers and builders need to adapt to?
The beginning of 2023 marked a downturn in the rental market in Limassol. Those who rent out properties hoped that tourists would come in the summer and that more large companies would relocate to the island in 2023, bringing some of their employees with them. But the miracle didn’t happen. There were rumours that the war with Hamas would force Israelis to move to Cyprus, meaning they would rent and buy property.
However, the Israelis who did arrive tend to rent the most affordable properties, as they plan to return to Israel as soon as possible. The usual Limassol segment of luxury or (even) business-class properties doesn’t interest them.
Can we expect any changes?
From experience, I can say that the real estate market is prone to fluctuating up and down approximately every one and a half years. This is due to global economic processes, currency rate dynamics, military actions, the pandemic, and so on. There will definitely be a rise. I expect it around the middle of 2024. I think the interest in renting is stimulated by changes that have occurred in Cypriot legislation.
How significantly have rental prices in Limassol fallen?
I would say by 30%. In some cases, even 40%. That’s a lot. Clients have plenty to choose from, as the market has seen new, recently-built houses and apartments. New housing competes with secondary market properties, and as of today, supply has greatly exceeded demand. However, I believe that in 2024, rental prices will increase again, and a balance between demand and supply will be restored.
Is the situation similar in the sales sector?
For professionals in the real estate sector, the picture is much more positive regarding sales. Many large investors have turned their attention to Cyprus. They have specific requests: now, investors want to purchase projects that are ready for execution and have obtained all construction permits. The average investment cheque for such projects is around 3 million euros.
What kind of property is currently in demand?
The greatest interest is in two-bedroom apartments costing up to 450,000 euros. In second place are three-bedroom apartments not exceeding 800,000 euros. I try very hard in my projects to fit into this price segment. One-bedroom apartments in Limassol are often purchased on credit, people take loans from banks. In this case, the buyers are looking at properties ranging from 135,000 to 185,000 euros in the economy class segment: this is quite affordable housing without heating and often built without using quality thermal insulation materials.
Is the demand for buying apartments higher than for buying houses?
Yes, definitely. Currently, 70% of enquiries are specifically for apartments. Houses, especially in Limassol, are not cheap. For example, five years ago, you could buy a house for between 380,000 and 450,000 euros. Now, the average cost of a house is 1 million euros. And that’s far from the best option; such houses often require major repairs.
What are the trends in the Cypriot real estate market in 2024? What will happen with sales?
Changes in the citizenship acquisition legislation will greatly affect the market. And they are already having an impact. This will attract digital nomads who are hesitating between living in Thailand, Malta, and Cyprus. They will be coming here.
Additionally, I believe that Cyprus joining the Schengen Area is not far off. We mustn’t forget the tax advantages. I know of at least five companies seriously considering relocating to Cyprus because of these reasons.
This indicates that demand for modern, quality housing will not decline. Despite everything happening in the world, people continue to earn money, buy property, and invest in construction projects. It’s clear that buyers are evaluating the market to see who is working conscientiously and who is just in it for a quick profit.
What does this mean?
Now, construction companies really need to work well on their product and think through the details, as the buyer has become more demanding. It’s necessary to increase room sizes, create storage systems (remember when our homes had built-in wardrobes, storerooms, and mezzanines?). If the product is well-thought-out and made for people’s convenience and comfort, it will sell well (of course, if it has a reasonable price).
What else is lacking on the island in terms of real estate?
There’s a lack of a certain community that would help create products based on public opinion. I think any construction company would be interested in this. We also lack initiative groups to qualitatively improve our cities. Much needs to be organised through the state, philanthropists, and businessmen who live here and benefit from tax advantages. It’s easier to sell in beautiful cities.
Can you tell us about your activities in 2023? And what are your plans for 2024?
In 2023, I took on three projects. The first project, named Elvis, is a modern complex building comprising 11 apartments and two magnificent penthouses. This building is designed for the Russian-speaking target audience, prioritising quality heating systems and high three-metre ceilings. Our complex is located near a municipal park. It faces low-rise buildings, so all apartments have a beautiful view. The project is expected to be completed by July 2025.
The second project is called ‘Diamond Valley’. It’s a club village in the Agios Tychonas area, currently in the early stages of construction. It will be completed in exactly two years, possibly even earlier. There are 45 apartments for sale, including studios, one-, two-, three-, and four-bedroom apartments. The exterior facades of the buildings resemble villas or townhouses. It looks very modern. The roof slopes resemble the facets of diamonds, hence the name ‘Diamond Valley’. This project will feature luxurious infrastructure: a large swimming pool, sauna, beauty salon, kiosk, gym, co-working area, dietician’s office, yoga corner, café, a modern large hall for various events, and round-the-clock security.
The speed of construction is impressive. All this in two years...
Yes, we strive to build quickly without compromising on quality, paying due attention to each construction stage. And I want to emphasise: our prices are very affordable. A studio can be purchased from 210,000 euros. Three-bedroom apartments from 875,000 euros. This is incredible for projects with such a level of infrastructure.
Tell us about your third project...
It’s not just a project. It’s a new construction company with an innovative approach to each project. We called it Real Onyx Development Group. Our first project is a building named Fancy Urban near the Era shopping centre on Makarios Avenue. Cyprus has not seen such facades before. It’s an absolutely innovative design and layout.
Why is your company called ‘Real Onyx’?
While studying at University, I read a lot about various finishing materials and panels. Onyx particularly caught my attention. It is hardly used in Cyprus due to its high cost. But it has healing properties, relaxing after a hard day, helping with insomnia, relieving stress. Therefore, we use onyx in bathroom finishes, showers, and kitchen countertops. Essentially, such an apartment will aid in recovery.
We have two more projects planned, but they are unnamed so far, only the location has been determined, near Ygia Polyclinic and Papas Supermarket. Prices are affordable: one-bedroom apartments start from 235,000 euros plus VAT. This is a brief overview of our plans for 2024.
I hope the coming year will be successful for everyone working in the real estate sector in Cyprus! And for buyers and renters, it will be a good year as there will be even more options for choosing suitable housing.
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According to the official Cyprus House Price Index, the first quarter of 2023 showed a quarterly increase of 2.1% and an annual increase of 7.7%. Prices for residential real estate grew most significantly, particularly, apartment prices increased for the seventh consecutive quarter. One of the reasons is the country’s new policy, requiring foreign companies operating in Cyprus to relocate their headquarters to the island. As a result, company owners, managers, and other employees start looking for accommodation. By August 2023, foreigners and expats from non-European Union countries accounted for a third of all sales. Property sales increased by 15% in September 2023, reaching 1,336 transactions compared to 1,157 in the same month of 2022. From January to September 2023, the total number of sale agreements filed across Cyprus was 11,519
compared to 9,610 for the same period last year, representing a 20% increase.
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Anfisa Chernaya
Expert in Cypriot real estate, leader of construction projects in Limassol, and head of the marketing agency Digital Factory. Born in Moscow, she graduated from school with a gold medal and obtained a higher education degree in ‘State and Municipal Administration’. In 2023, she graduated from Neapolis University in Paphos, earning a master’s degree in ‘Real Estate’.
With over 20 years of experience spanning across 70 jurisdictions, Isavella Korelidou-Evripidou offers an insider’s perspective on the shifts in Regulatory services, brokerage licenses, the introduction of crypto regulations, and the future of e-gaming and betting in the country. Her insights reveal both the challenges and opportunities lying ahead for investors and businesses navigating Cyprus’ financial industry.
Let us overview, sector by sector, some of the most crucial areas of your expertise. What changes can we expect in the field of brokerage licenses in 2024?
Cyprus continues to lead with a significant number of Brokerage companies in Europe, especially those dealing with CFDs. However, due to newer, stricter regulations from European bodies like ESMA, the industry faces challenges. Some countries are increasingly hesitant to work with CFDs due to their high-risk nature. As a Licensed award-winning Service Provider, we attract many investors to Cyprus.
We’re observing a shift in Cyprus, with companies beginning to include or switch to classical brokerage. This transition allows clients to trade on stock markets, a less risky option compared to CFDs. It’s a positive development that broadens the choice for clients seeking reliable brokerage firms.
How about the cryptocurrency field? Are there any significant legislative changes?
Absolutely. This year we have seen the implementation of the MiCA regulation (Regulation 2023/1114), which ratifies the way the Crypto industry should be regulated. This regulation was much needed. While it introduces certain restrictions, it also means that compliant companies can establish greater trust with their clients. Overall, it’s a step forward for the industry.
What’s on the horizon for investment fund licensing?
Cyprus is very attractive to Investment Funds structures, where a new type is potentially arriving in 2024. These new structures are expected to be more appealing to investors, offering innovative investment opportunities. It’s an exciting time, with potential advancements that could significantly enhance the attractiveness and efficiency of investment funds. The future of investment fund licensing is characterized by a dynamic and evolving landscape, shaped by technological advancements, changing investor preferences, and regulatory reforms. Investment fund managers and regulators must adapt to these changes to ensure that the industry remains innovative, competitive, and well-regulated.
Could you share insights on the e-gaming and betting field in Cyprus and any upcoming changes in licensing?
Cyprus has no regulation for e-gaming yet, but fully regulates the Betting, which is very attractive to many investors who want to establish their business on the Island and we assist them with that.
Currently, Cyprus Betting licenses are regulated by the National Betting Authority (NBA), where 2 types of licenses are given: Class A and Class B. Class A requires to have a fully operational office in the Country, where the Class B allows to run the business on-line.
Another significant addition we’re anticipating is the inclusion of online gaming, which would represent a major development for Cyprus. However, due to a history of unregulated online casinos, the current approach to legislation and regulation is quite stringent.
What activities fall under the category of online gaming?
Online gaming encompasses a wide range of activities that involve playing games over the internet. These activities can be broadly categorized into different types of games, such as multiplayer games, single-player games, and casual games.
What makes Cyprus attractive to EMI businesses, and how does Cyprus compare to competitors like Malta?
Cyprus, a small island country in the Eastern Mediterranean, has emerged as an attractive destination for EMI (Electronic Money Institution) businesses. Cyprus faces competition from other European countries, particularly Malta, which is also an attractive destination for EMI businesses. Cyprus is an attractive destination for EMI businesses due to its regulatory environment, tax incentives, geographic location, skilled workforce, and stable economy. However, it faces competition from countries like Malta, which has a more established FinTech sector and a more favorable tax regime. Both countries offer unique advantages to EMI businesses, and the choice between the two will depend on the specific needs and objectives of each business.
GFSC Global is an award-winning, International Corporate and Legal Services Providers, licensed in the EU and other jurisdictions, with over 20 years of experience in Corporate, Legal, Immigration, Gaming, Financial, Crypto/STO/ICO, Banking and Accounting services. Its main goal is to offer a full range of high quality, tailor-made services to our corporate and physical clients worldwide through our qualified team of professionals.
Our mission is to provide a full package of services as a one–stop–shop solution, including company formation, re-domiciliation, opening of bank accounts, administrative services, immigration, legal support, licensing (Forex/Brokerage, Investment Funds, Crypto, STO/ICO, Betting/Gaming, Payment services/EMIs, Banking) and post-licensing services (Compliance, AML, Reporting, Risk Management, Reporting, Internal, and External Audits).
Our global presence spans over 70 jurisdictions, giving us a nuanced understanding of international legislation and the ability to craft cross-jurisdictional structures for our clients.
Great Place To Work® is the global authority on workplace culture. With a presence in 90 countries, it surveys, every year, 10,000 companies and uses these survey insights to define what makes a great workplace experience.
It helps organizations quantify their culture and produce better business results by creating a high-trust work experience for all employees. The certification badge and recognition practices help companies showcase their workplace culture and enhance their employer branding.
For HR leaders, there are few milestones that hold as much pride as becoming Great Place To Work-Certified™. It signals to the world that they have created a company culture that employees love.
When you become Certified, you earn more than just a shiny badge.
These are the 5 reasons why companies choose to become Great Place To Work-Certified™.
1. Recruit top talent and increase your offer acceptance rate
Recruitment and especially attracting top talent is increasingly becoming a major challenge especially in some industries. Improving the company’s Employer branding is now essential. The globally recognized Certification badge acknowledged as the most credible accreditation of premium employers is an invaluable asset for the Employer branding.
Great company culture is now a prerequisite for job seekers. They are using Certification to help them validate employer claims and weigh up job offers.
Certification signals that current employees endorse their organization’s culture and leadership. It tells candidates that employees feel supported and would recommend their workplace to others.
Great Place To Work customers who have been creatively using the certification badge in their communication mix confirm that both the quantity and quality of interest and applicants interested in their job openings increases.
Great Place To Work will celebrate and showcase your success on its social media platforms and in cooperation with its media partners, The Phileleftheros Group.
Every Certified company earns a profile presence on the Great Place To Work website. You can share company details and any other recognition earned on the Best Workplaces lists. Certified companies often link to their profile from their careers page to provide third-party validation of their exceptional company culture.
2. Measure and improve your company culture against specific metrics
Certification depends mostly on the results of your Trust Index™ survey – the industry standard for measuring employee experience.
Upon collecting your employee survey responses, you will receive an in-depth analysis of your company culture. You’ll get insight into areas such as perceived fairness, feelings of belonging and perception of leadership.
The survey analysis step in Certification gets you inside the heads of your people and will give you a clear view of your culture strengths and areas of opportunity. Experience demonstrates that the analysis encourages and facilitates companies to embark on a continuous improvement process. Once your company is Great Place To Work-Certified, you will automatically be considered for inclusion in its Best Workplaces lists. Successful recognition on these lists creates more opportunities to stand out as a top employer.
3. Build employee pride
All employees want to be part of something special. Getting Great Place To Work-Certified builds pride among your workforce.
People are who you tell them they are. If you tell someone they are great and worthy, they’re going to aspire to be great and worthy. If you continue to tell your team members you are a great place to work, they will continue to make your company a great place to work.
Raising awareness of your Certification among current employees is akin to promoting your company values, mission, and culture. Certification reinforces that you are a company that cares. A company that puts people first.
Because employee opinions dictate the results – it’s a reminder that, yes, your company is a great place to work. Earning Certification is a cause to celebrate – a reason to thank your employees. So, rally your team around this win and celebrate – Great Place To Work has many ideas to help you do this.
4. Add more value to your corporate image
Companies share the news of their Certification success with key stakeholders, such as customers, suppliers, and partners. This effectively demonstrated to them that the company has a positive workplace culture, and this positively impacts the way the company does its business and interacts with its stakeholders
5. A low cost and simple to manage process
All these benefits are the result of a low-cost process – a tiny fraction of the payroll cost. Being a digital process makes the work input on behalf of the customer minimal. The designated Customer Success Manager assigned to each customer makes sure that this is a trouble free, efficient and enjoyable journey.
As you can see, recognition is just the cherry on the sundae with Certification. Make your employees proud, recruit top talent and find gaps in your HR policies.
To learn how to get Great Place To Work - Certified™ visit www.greatplacetowork.com.cy or call at 22 364 777.
Materials are presented by Great Place To Work®
Кабинет министров Кипра одобрил законодательство о внедрении на Кипре европейской голубой карты – аналога американской грин-карты в странах Евросоюза. Схема по выдаче такого типа ВНЖ направлена на поощрение переезда в Евросоюз высококвалифицированных работников – граждан третьих стран.
«Предлагаемые изменения направлены на принятие более гибких рамок для въезда и проживания высококвалифицированных работников из стран, не входящих в ЕС. Вводятся более гибкие условия прибытия в страну, расширенные права, облегчение передвижения и работы внутри всего Евросоюза», – пояснил министр внутренних дел Константинос Иоанну.
Высококвалифицированными считаются работники, получившие высшее образование по учебной программе продолжительностью не менее трех лет. Также к ним относятся менеджеры и специалисты в сфере информационных и коммуникационных технологий с трехлетним профессиональным опытом в течение семи лет, предшествовавших подаче заявления.
Голубая карта действует в 25 странах ЕС, то есть по всему блоку, кроме Дании и Ирландии.
Подробнее о программе по ссылке.
О том, на каких условиях программа предоставления голубой карты реализуется в других странах ЕС, можно прочитать здесь.
Текст подготовлен по материалам Cyprus Mail
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Инновационная программа по обучению гостеприимству появится в начальных классах кипрских школ. К такому соглашению пришли Кипрская ассоциация отельеров, Министерство образования и Подминистерство туризма.
Учебная программа «Мое гостеприимство» (греч. «Филоксения му») была разработана Гостиничной палатой Греции в сотрудничестве с HOTREC, чтобы познакомить учеников с концепцией гостеприимства, предпринимательства, принятия и инклюзивности, инновационного и экологичного развития гостиничного бизнеса. Она поможет в первом знакомстве с профессиями сферы туризма и с возможностями карьерного роста. Лицензию на преподавание этой программы в школах Кипра передало Кипрской ассоциации отельеров Министерство туризма Греции.
Министр образования Афина Михаилиду выразила готовность своего ведомства воспользоваться преимуществами этой программы и в ближайшее время приступить к процедурам ее адаптации под кипрскую специфику и к внедрению в школы.
Глава Подминистерства туризма Костас Кумис, в свою очередь, подчеркнул необходимость преподавания аналогичной программы и в старших классах. Он отметил, что Министерство образования и Подминистерство туризма совместно установят контакты с Министерством образования, конфессий и спорта и Министерством туризма Греции для обмена опытом в этом направлении.
Председатель Кипрской ассоциации отельеров Фанос Михаилидис поблагодарил министра образования и главу Подминистерства туризма за большой интерес, который они с самого начала проявили к интеграции программы «Мое гостеприимство» в школы Кипра. По его мнению, это поможет устойчивому развитию туризма, значительно расширит горизонты и возможности нового поколения, одновременно способствуя пониманию и усвоению концепции гостеприимства как такового.
Текст подготовлен по материалам «Филелефтерос».
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Всего 14% поверхностей крыш промышленных объектов на Кипре используется под фотоэлектрические панели. К такому выводу пришло исследование с участием преподавателей из лимассольского университета Frederick.
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Более широкая установка фотовольтаики на крышах промышленных зданий может внести значительный вклад в сокращение выбросов парниковых газов и производство энергии из возобновляемых источников. Согласно результатам работы, потенциал поверхностей промышленных крыш может покрывать до 19% от потребности предприятий в электроэнергии и 2,7% от общего объема электроэнергии на Кипре. Однако сегодня реализуется только 14% этого энергетического потенциала. Авторы научной работы также предлагают конкретные меры финансовой поддержки установки фотоэлектрических систем на крышах промышленных предприятий с учетом долгосрочной выгоды для экономики Кипра.
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In this interview, George Xydas, founder of the Swissmed Health in Limassol, shares insights into his pioneering approach to longevity and personalised medicine. Opened last December, the clinic stands out in the European region for its unique focus on early detection, prevention, and treatment of aging-related issues. Delving into their holistic methodology, Xydas discusses the clinic’s comprehensive diagnostics, collaboration with leading labs, and a team of experts dedicated to personalized care. Swissmed Health’s approach is not just about treating diseases but enhancing life quality and extending health-span through advanced medical interventions.
Let’s discuss your new longevity clinic, a first of its kind in Cyprus, opened in Limassol last December. This clinic represents a shift in medical science from treating diseases to early detection and prevention, doesn’t it?
Indeed, we’re not just pioneering in Cyprus but also in the broader European region. Similar centers are in Germany, Switzerland, and the US, but ours is unique in the Mediterranean.
Our approach differs from traditional medicine, which usually diagnoses diseases based on symptoms. We focus on the underlying causes, taking a holistic view of the body. We personalize treatments for each patient, offering tailored medical interventions.
Could you elaborate on how you identify potential health issues? Is there a comprehensive body checkup involved?
Our process begins with advanced diagnostics, collaborating with leading labs in the US and Switzerland. We conduct thorough evaluations covering brain, cardiovascular, gastrointestinal health, genetic makeup, and environmental factors. This comprehensive analysis gives us a detailed health map for each individual. Based on these findings, we develop a personalized medical plan tailored to the patient’s unique genetic profile.
Who are the experts interpreting the results of your diagnostics?
Our team includes four full-time licensed medical doctors, each specialized in a different field, yet retrained to view patients holistically. We also collaborate with global medical leaders, providing insights for unique cases and conditions.
Could you describe the clinic’s role in Limassol and how it compares to international counterparts? What inspired this concept?
Our clinic’s concept is twofold. For 25 years, we’ve treated complex conditions, and in the last three years, we’ve closely followed global longevity research, focusing on slowing, stopping, or reversing aging. We noticed a gap in clinical longevity implementation within the European Union, as there are no clinics specializing in this area with medical interventions.
Comparatively, we could be likened to certain clinics in Switzerland providing mostly lifestyle treatments. However, while they focus on nutrition, sleep, exercise, and lifestyle, we delve deeper, incorporating these aspects but also engaging in direct medical interventions. We address the pillars of aging, offering a more comprehensive approach to longevity.
What are the seven pillars of aging?
The seven pillars of aging start with genetics, our DNA. The second is epigenetics, how environmental factors such as toxic substances affect us. Thirdly, we consider inflammation. The fourth pillar is mitochondria, essential for energy. Fifth comes cell regeneration, closely tied to stem cell therapies. The sixth is senescent cell apoptosis. Our body sheds cells daily, but not all are efficiently removed. These lingering senescent cells can lead to various conditions, including cancer. Lastly, the seventh pillar is telomere extensions. Telomeres, located at chromosome ends, shorten as we age. These seven pillars collectively encapsulate the key aspects of aging. Of course, as research on aging reversal continues, new studies are published frequently on new reasons for aging and potential ways to decelerate the process, emerge.
How can we address aging? After diagnosis, do you work on slowing down the aging process?
Absolutely. Our approach to life extension starts with addressing diagnosed or undiagnosed conditions, with or without symptoms. Initially, we focus on resolving present issues. Following this, we guide our patients on a path towards long-term longevity, aiming to live a healthier life today, and decelerating the aging process.
We utilise specialized diagnostics to monitor the aging process. Biological clocks assess biological age irrespective of chronological age. Post-treatment, we reevaluate to see if the biological age has been reduced.
People often view such diagnostics and tests as expensive. Do you offer any packages for newcomers?
Indeed, we provide various packages, including comprehensive health assessments, personalized to each person, typically divided into core and enhanced categories based on personal goals. For longevity treatments, we offer a membership program for ongoing care. This memberships include doctor consultations, starting from monthly, to unlimited visits, deep detoxification programs, performance enhancement and options for diagnostics conducted once, twice, or three times a year.
What would be your flagship treatment? What would be really something that people will talk about immediately as soon as they visit the clinic?
Our Lifespan treatments that focus on proactive cognitive decline and performance enhancement. Research highlights the importance of early intervention in cognitive impairment prevention From age 35 onwards, individuals should consider preventive protocols for cognitive health.
Performance enhancement varies per individual, encompassing sports, life, and hormonal health, including sexual health. Our cognitive health protocol and performance treatment plans are key elements in promoting longevity and lifespan. For health-span, we address conditions prevalent among our patients, such as autoimmune diseases, cancer, and other complex conditions.
What else do you want to mention in addressing the expat community of Cyprus?
There is a centre in Cyprus that brings Swiss personalized medicine to the forefront. Our treatments consider the body as a whole, rather than focusing on specific symptoms or generalised health approaches. We offer personalized medical services tailored to help individuals maintain their health, live longer, and improve their quality of life. Our goal is to ensure holistic well-being for a healthier, extended life.
The Clinical & Translational Omics Symposium 2023 was held in Protaras on November 4-5th, 2023 It brought together researchers from the fields of Omics, including proteomics, metabolomics, and lipidomics, along with experts in bioinformatics and the application of artificial intelligence. These experts played a crucial in translating omics findings into clinical research and practice. We spoke with one of the leading international experts in the area of clinical proteomics, Dr. Jennifer Van Eyk Director of Basic Science Research at the Barbra Streisand Women's Heart Center, Cedars-Sinai Medical Center, USA.
Could you explain, in simple terms, how advancements in clinical proteomics impact medical treatments and patient care?
Let’s first say a few words about Omics, in general. Lots of people don't know what proteomics is, although almost everyone does know what their genome.
The genome, or your DNA, can be thought of as a city map. If you had a map showing only the highways, streets and buildings, that's your genome. But, if you add to the map the roads and highways, with everybody's walking around, and the cars that are coming and going, then this dynamic city is the proteome. If you have an accident on one of your highways, then you have first responders come. That's how your proteins work inside the cells, they respond and change when you have a disease. So the proteome can be thought of as a highly responsive. That's really how proteins work – they are what brings the ‘city’ alive.
In proteomics we try to measure all proteins and also their cellular location and activity. Of course, we are not able to do everything. We wish we could, and that is why technology becomes so important. Today, the technology challenge is sensitivity. Trying to see a protein in a cell, is like sit on the rings of Saturn and look down into a room and figure out who is wearing glasses and who is not. It gets more complicated because if I look today and you're wearing a blue suit with glasses, but tomorrow, you might be wearing a brown suit with sunglasses. Proteins are like that, they can change. That's why it's so hard but it is what makes the “city” alive and proteins is what makes each one of us alive.
To come back to your question. How proteomics impact medical diagnostic and treatments – well, proteomics is impacing both sides. Proteomics helps to determine if you're sick, and it can tells you how you're going to respond to a drug. It will also tell you what your chances of survival are.
Today, you can take a little finger prick of blood, wick it up, and mail it to us for analysis using proteomics. Then, based on the proteomic we can tell how your are progressing over time. You don't have to go see your doctor. You can collect your blood sample anywhere; at home or if you're on vacation, or in a remote part of the world. As a consumer this will give you an ability to track your health and your wellness.
How might these advancements influence or benefit businesses in the healthcare sector or related industries?
There are lots of opportunities – from being able to help consumers to directly track their health, reduce the cost within a hospital or the medical system and help develop new drugs that you need. Based on remote blood sampling devices, maybe you can see how this technology can be combined with telehealth to reduce the cost of health care while providing better health service. It can mean that when you're doing drug trials, instead of having everyone come in physically to have a blood samples taken, the person can do it from home. Today it is normal in drug trials that the whole population is not represented, instead only a certain demographics are. Now with remote blood sampling devices, we can reduce that barrier, and have results from even populations that are rare, from different backgrounds.
Over the next 10 years, doctors and pharmacies will start to see proteomics impact diagnostics and availability of drugs. They may not see it in an everyday practice, but it is and will continue to happen. For business professionals, it will be important to understand in order to invest in proteomics and the diagnostics and drugs that come from proteomic research. This means that we need to have educational or awareness-building initiatives would you recommend bridging the knowledge gap in proteomics and its business applications?
Education is fundamental. It is important to science education throughout school including high school students come and work in people's labs. Science needs to be there discussed in every part of life. It is also important to allow opportunities to ask questions in both directions. Professionals on the investment side need to be able to ask questions so that they know where to invest. They should have the possibility to talk to scientists. As well, scientists should able to ask business professionals how to move an idea to a commercial produce. This needs to be a continuous discussion.
Science technology moves so quickly. Today what is possible to do in research or what the new instrument and technologies, 10-15 years ago might have sounded as though they were part of a fantasy movie? It is sometime unbelievable how fast science and proteomic technology is moving. For example, we have this great study, it is called Molecular Twin.
In Molecular Twin, we have started with pancreatic cancer and measured all of the omics including the proteome of blood and the tumor. It turned out measuring specific proteins in plasma can tell you how will have cancer return (reoccurance). This can be used to determine when compared to others with pancreatic cancer what were successful treatment and help develop new drugs.
Our goal of developing diagnostics is that every time a physician has to make a decision, or every time a patient has to make a decision, there is a diagnostic that can provide quantitative data to help with that decision making. Having a diagnostic that allows you not to just guess, which is horrible, but to give you a information that is specific to you. That is precision medicine. This is what inspires me the most – it’s challenging but it could change the medicine.
Jennifer Van Eyk, PhD, is an international leader in the area of clinical proteomics. Her lab has focused on developing technical pipelines for de novo discovery and larger-scale quantitative mass spectrometry methods. This includes multiple reaction monitoring (MRM, also known as SRM) and, most recently, data-independent acquisition. Dr. Van Eyk's laboratory is well known for the extreme technical quality of the data generated, rigorous quality control with tight % CV while applying these to key clinical questions. The aim is to maximize throughput and reproducibility. This will facilitate the transition of targeted and robust discovery methods into large-scale assessments of healthy populations and clinical-grade assays, focusing on brain and cardiovascular diseases.
Какой налог придется уплатить при покупке недвижимости на вторичном рынке Кипра, и как правильно рассчитать данный сбор – рассмотрим в статье.
Между покупкой новой недвижимости на Кипре и приобретением вторичного жилья существует фундаментальная разница в налоговых начислениях.
При покупке недвижимости, на которую еще ни разу не было оформлено право собственности, в стоимость объекта будет включен НДС. О видах НДС на сделки с недвижимостью и правилах их начисления мы писали ранее.
При повторной продаже недвижимости НДС уже не начисляется. Вместо этого, в момент перерегистрации права собственности в Департаменте земельного кадастрового учета покупателем должен будет уплачен титульный сбор (Property Transfer Fee).
Титульный сбор рассчитывается следующим образом:
Если покупка недвижимости не облагается НДС, то при расчете титульного сбора действует скидка 50%.
Стоит учесть, что самостоятельно рассчитать сумму титульного сбора получится лишь примерно, а рыночная стоимость недвижимости может существенно отличаться от цены, согласованной продавцом и покупателем. Точную рыночную стоимость недвижимости сообщат в Земельном кадастре, где ведется статистика по сделкам купли-продажи в каждом городе и районе Кипра.
Если право собственности на недвижимость переходит к другому лицу без финансовых обязательств между сторонами сделки, то титульный сбор рассчитывается следующим образом:
· От родителей к детям – 0% от рыночной стоимости недвижимости
· Между супругами – 0.01%
· Между родственниками третьей линии – 0,01%
· От подопечного попечителю – 50 евро
Статья подготовлена по материалам компании PwC.
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